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. 2022 Mar 23;12:4942. doi: 10.1038/s41598-022-09117-9

Table 1.

Baseline characteristics of the patients.

Variables Total (n = 390) NKP failure group (n = 95) NKP success group (n = 295) p-value
Median age, years (range) 72 (21–96) 72 (27–93) 71 (21–96) 0.875
Male, n 204(52.3%) 51(53.7%) 153 (51.9%) 0.757
Indications of ERCP
Choledocholithiasis, n 220(56.4%) 56 (58.9%) 164 (55.6%) 0.566
Malignant biliary stricture, n 131(33.6%) 32 (33.7%) 99 (33.6%) 0.982
Benign biliary stricture, n 23 (5.9%) 4 (4.2%) 19 (6.4%) 0.422
Bile leak, n 14 (3.6%) 2 (2.1%) 12 (4.1%) 0.371
Sphincter of Oddi dysfunction, n 2 (0.5%) 1 (1.1%) 1 (0.3%) 0.397
Median CBD diameter, cm (range) 1.2 (0.4–4.1) 1.2 (0.4–4.1) 1.2 (0.4–2.9) 0.866
Major papilla status
Periampullary diverticulum, n 80 (20.5%) 27 (28.4%) 53 (18.0%) 0.028
Enlarged or swelling, n 44 (11.3%) 12 (12.6%) 32 (10.8%) 0.633
Impacted stone, n 13 (3.3%) 0 (0%) 13 (4.4%) 0.037
Tumor, n 21 (5.4%) 7 (7.4%) 14 (4.7%) 0.325
Low set papilla, n 14 (3.6%) 3 (3.2%) 11 (3.7%) 0.795
Surgically altered anatomy, n 34 (8.7%) 13 (13.7%) 21 (7.1%) 0.049

CBD common bile duct, NKP needle-knife pre-cut papillotomy, ERCP endoscopic retrograde cholangiopancreatography procedure.