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. 2022 Mar 23;12:4942. doi: 10.1038/s41598-022-09117-9

Table 2.

Technique factors, and adverse events of needle knife pre-cut papillotomy.

Variables Total (n = 390) NKP failure group (n = 95) NKP success group (n = 295) p-value
Endoscopists, n 0.024
A 186 (47.7%) 37 (38.9%) 149 (50.5%)
B + C 142 (36.4%) 35 (36.8%) 107 (36.3%)
D + E 62 (15.9%) 23 (24.2%) 39 (13.2%)
Bleeding during NKP, n 47 (12.1%) 37 (38.9%) 10 (3.4%)  < 0.001
P-duct stent 39 (10%) 8 (8.4%) 31 (10.5%) 0.694
Early pre-cut 96 (24.6%) 21 (22.1%) 75 (25.4%) 0.514
Overall adverse events, n 27(6.9%) 4 (4.2%) 23 (7.8%) 0.496
Perforation 2 (0.5%) 1 (1.1%) 1 (0.3%) 0.397
Pancreatitis 4 (1.0%) 1 (1.1%) 3 (1.0%) 0.976
Delayed bleeding 13 (3.3%) 1 (1.1%) 12 (4.1%) 0.154
Cholangitis 8 (2.1%) 1 (1.1%) 7 (2.4%) 0.430

NKP needle-knife pre-cut papillotomy, P-duct pancreatic duct.