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. 2022 Mar 23;13(3):260. doi: 10.1038/s41419-022-04690-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — MCF-7 and MDA-MB-231 cells transfected with LV-GFP or LV-GNG2 as described in the Methods. A and B GNG2 expression at protein levels in MCF-7 (A) and MDA-MB-231 (B) cells. C and D Effect of GNG2 overexpression on cell viability in MCF-7 (C) and MDA-MB-231 (D) cells was detected by CCK-8 assay. E Effect of GNG2 overexpression on cell proliferation was determined by colony formation assays (n = 3). F and G Effect of GNG2 overexpression on cell apoptosis and cycle was measured in MCF-7 (F) and MDA-MB-231 (G) cells by flow cytometry analysis (n = 4). Data are expressed as the mean ± SD. * p < 0.05, ** p < 0.01 vs. GFP.