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. 2022 Mar 23;13(3):260. doi: 10.1038/s41419-022-04690-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Female nude mice were subcutaneously injected with LV-GNG2- or LV-GFP-infected MCF-7 or MDAMB-231 cells as described in Methods. A Photos of the tumor-bearing nude mice and the xenograft tumors dissected from the nude mice. B and C Tumor growth curves in nude mice injected with MCF-7 (B) and MDAMB-231 (C) cells. D and E The weight of xenograft tumors from mice injected with MCF-7 (D) and MDA-MB-231 (E) cells (n = 4). F and G Immunohistochemical analysis of Ki67 protein in tumor tissues transfected with GNG2-overexpressing MCF-7 (F) and MDA-MB-231 (G) cells (magnification of 400×), Scale bars, 50 μm. Data are expressed as the mean ± SD. * p < 0.05, ** p < 0.01 vs. GFP.