Table 1.

Characteristics of participants at baseline and follow-up time of neuropsychological evaluation sorted by PiB status.

	Aβ−	Aβ+	P value
n, No. (%)	92 (71.9)	36 (28.1)
Age (years)	66.75 [62.69, 72.69]	76.62 [71.00, 82.38]	<0.001	***
Sex, No. (%) = M	40 (43.5)	17 (47.2)	0.853
Education (years)	16.00 [14.00, 18.00]	16.00 [13.00, 18.00]	0.946
PiB, PVC FLR (DVR)	1.18 [1.14, 1.21]	1.84 [1.50, 2.16]	<0.001	***
MMSE (score)	30.00 [29.00, 30.00]	29.00 [29.00, 30.00]	0.051
GDS (score)	2.00 [1.00, 4.00]	2.00 [1.00, 4.00]	0.889
Logical Memory delayed-recall (score)	14.00 [12.00, 16.25]	15.00 [12.00, 17.00]	0.271
PACC5 (score)	0.32 [−0.10, 0.57]	0.03 [−0.32, 0.52]	0.113
NP follow-up time (years)	4.10 [2.03, 8.23]	6.92 [3.92, 8.33]	0.025	*

Data are presented as medians and [interquartile ranges (IQRs)] for continuous variables and proportions for dichotomous data. Two-tailed chi-square tests and Kruskal–Wallis tests were conducted to evaluate group differences.

DVR distribution volume ratio, FLR frontal, laterotemporal and retrosplenial cortices, GDS Geriatric Depression Scale, M male, MMSE Mini-Mental State Examination, NP neuropsychological evaluation, PVC partial volume corrected, PiB Pittsburgh Compound-B, PACC5 Preclinical Alzheimer Cognitive Composite.

*p < 0.05, ***p < 0.001.