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. 2022 Mar 14;9:445–469. doi: 10.1016/j.toxrep.2022.03.011

Table 3.

Mechanisms of antioxidant activity of flavonoids.

Responsible structural elements Mechanisms of antioxidant activity References
4-(-C = O) group in conjugation with 3-OH group Metal chelating activity [207]
4-(-C = O) group with 5-OH group
3′,4′-OH groups
3′,4′-OH groups Scavenge Peroxynitrite [210]
3-OH group
Flavones structure Inhibit protein kinase C [210]
7-OH group
3′,4′-OH groups
3′,4′-OH groups Scavenge ROS [207]
3,5,7-OH groups
4-(-C = O) group in conjugation with 2,3-double bond