Table 9.
List of flavonoids with gastroprotective effect and their mechanism of action.
| Flavonoids | Mechanism of action | Ref |
|---|---|---|
| Flavones and flavonols | Inhibit H. pylori | [164] |
| Artemisin | Bactericidal kinetics | [42] |
| Morphological degeneration | ||
| Pinostrobin \ | Decrease gastric motility | [2] |
| Catechin | Urease inhibitor | [171] |
| Anti-inflammatory | [251] | |
| [226] | ||
| Isorhamnetin | Inhibit ulcer | [289] |
| Eradicate H.pylori | [259] | |
| Curcumin | Inhibit proton potassium ATPase | [294] |
| Chemo-preventative | [112] | |
| 4-methoxy quercetin-7-O-glucoside | Chemopreventive | [220] |
| [103] | ||
| Glabridin | Anti-adhesive activity | [17], [279] |
| Inhibit dihydrofolate reductase | ||
| Inhibit DNA gyrase | ||
| licoricidin | Chemopreventive agents | [71] |
| [11] | ||
| Leucocyanidin | Increase mucus | [145] |
| [113] | ||
| Cabreuvin | Inhibit NADH oxidation | [190] |
| Baicalein and chrysin, | Gastroprotective | [15] |
| [249] | ||
| Vitexin | Release myeloperoxidase Inhibite H+ ,K+ ATPase activity N- | [215] |
| Acetylation | ||
| Quercetin | Anti-inflammatory | Wang et al., 2015 |
| Antiulcer invivo | ||
| Analgesic | ||
| Emodin | Damage DNA H. Pylori | [271] |
| Kampferol | Reduce gastric PH | [169] |
| Participate No and SH | ||
| Rutin | ulcer-protecting effects against gastric lesions | [136] |
| Resveratrol | Chemopreventative | [204] |
| Antioxidant | ||
| 7-carboxymethyloxy-39,49,5-trimethoxyflavone | suppresses the H. pylori–induced IBD by targeting NF-kB and ERK | [267] |
| [109] |