FIGURE 8.

Descriptive images of immunohistochemically stained pulmonary arteries for VE-cadherin (magnification 20×): a) normal control (NC), b) idiopathic pulmonary fibrosis (IPF), in insets junctional and cytoplasmic expression of VE-cadherin in NC and IPF, respectively (100×). Staining images for: N-cadherin c) NC and d) IPF (20×); S100A4 e) NC and f) IPF; vimentin g) NC and h) IPF; α-SMA i) NC and j) IPF; collagen-I k) NC and l) IPF; and collagen-IV m) NC and n) IPF (all images taken in 20× magnification for medium-size arteries). The black arrows indicate mesenchymal protein expression in the intima, and the red arrows indicate α-SMA+ myofibroblast (in inset intima) and ECM protein: collagen I and collagen IV deposition (in inset intima).