Table 1.
Summary of Sample Sizes and Biological Replicates for Each Experiment.
| Experiment | Panels | Number of Replicates | Age of mice & Strain |
|---|---|---|---|
| NPC 5DIV Differentiation In vitro |
1D-G | 3-5 biological replicates | P7, CD1 |
| S1 | 4 biological replicates | ||
| NPC 7DIV 2° Neurospheres In vitro |
2B | 3 Biological replicates 9 Technical replicates |
P7, CD1 |
| NPC 1DIV Proliferation In vitro |
2D-F | 5 biological replicates | P7, CD1 |
| 2G | 4 biological replicates | ||
| NPC 3DIV Proliferation In vitro |
2I-M | 3 biological replicates | P7, CD1 |
| 2N | 4 biological replicates | ||
| 2O | 3 biological replicates | ||
| OPC 2 + 3DIV Differentiation In vitro |
3C-D | 5 biological replicates | P7, CD1 |
| 3E | 4 biological replicates | ||
| 7E | 3 biological replicates | ||
| 24hr Injection NPC Proliferation In vivo |
4C-H | 3 animals/condition from two independent litters | 3-month old, NestinCreERT2; RosaYFPSTOP |
| 7 Day Infusion NPC Proliferation In vivo |
5C-J | 3-4 animals/condition from two independent litters | 3-month old, NestinCreERT2; RosaYFPSTOP |
| 7 Day Infusion OPC Proliferation In vivo |
5L-Q | 3 animals/condition from two independent litters | 3-month old, NestinCreERT2; RosaYFPSTOP |
| 7 Day Infusion Differentiation In vivo |
6C 6E-F 6H-I |
3-4 animals/condition from two independent litters | 3-month old, NestinCreERT2; RosaYFPSTOP |