Table 3.

Uni- and multivariable cox regression analysis of predictors of disease-free survival.

	Univariable Analysis		Multivariable Analysis
Characteristics	Hazard ratio (95% CI)	P Value	Hazard ratio (95% CI)	P Value
Age	0.999(0.981–1.017)	0.924
BMI	0.971(0.921–1.022)	0.267
Sex (female vs. male)	0.784(0.518–1.185)	0.248
Tumor differentiation
Well and moderate	Ref		Ref
Poor	1.809(1.182–2.769)	0.006	1.740(1.129–2.680)	0.012*
Pre-CRT CEA (≤5 vs. >5)	1.235 (0.873–1.748)	0.234
Pre-CRT CA199(≤20 vs. >20)	1.385(0.939–2.044)	0.101
Location (%)
Cardia	Ref		Ref
Corpus	1.473(0.960–2.261)	0.076	1.132(0.731–1.753)	0.579
Antrum	1.170(0.736–1.861)	0.506	1.256(0.786–2.010)	0.340
Diffuse	2.768(1.507–5.083)	0.001	2.830(1.524–5.254)	0.001*
Clinical T stage
T2 and T3	Ref
T4a	1.298(0.888–1.897)	0.177
T4b	2.025(1.013–4.048)	0.046
Clinical N stage
0	Ref		Ref
1	1.070(0.544–2.105)	0.844	0.870(0.437–1.732)	0.692
2	1.196(0.620–2.306)	0.593	0.871(0.444–1.710)	0.688
3	2.893(1.544–5.422)	0.001	2.378(1.250–4.524)	0.008*
DLRN (low vs. high)	0.446(0.256–0.778)	0.004	0.500(0.283–0.886)	0.018*