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. 2022 Mar 21;10:23247096221086453. doi: 10.1177/23247096221086453

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© 2022 American Federation for Medical Research

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Pulmonary tumor embolism: (A) H&E 10×: H&E-stained slide showing tumor cells (asterisk) within the lumen of a muscular artery, causing venous congestion without intimal proliferation, (B) Immunostaining for CK-7, 10×: CK-7 positive tumor cells (black arrowheads) in the lumen of blood vessels, and (C) Immunostaining for SMA, 10×: tumor cells (outlined in black) within the lumen of the artery without causing intimal proliferation. SMA staining is confined to the original wall of the artery and not extending into the lumen.

Abbreviation: SMA, smooth muscle actin.