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Schematic representation of common challenges in transporting MOF-NZ nano-/micro-motors in cancerous tissue. A The presence of corona proteins on the motors reduces the possibility of penetration into tumor tissue. B Increasing the size of the motors reduces access to the depths of cancerous tissue due to the reduction in capillary thickness and C One way to eliminate the motors is to use the immune system to digest them in the digestive vesicles and convert into non-toxic elements
