Table 5.
Comparison of uRDT and cRDT sensitivity stratified by parasite density (p/µL) as determined by TBS
| Group density (p/µL) | # samples TBS (+) (reference) | uRDT (+) | uRDT sensitivity (95% CI) | cRDT (+) | cRDT sensitivity (95% CI) |
|---|---|---|---|---|---|
| < 1 | 0 | 0 | – | 0 | – |
| 1–10 | 15 | 5 | 33% (12–62) | 2 | 13% (2–40) |
| 11–50 | 5 | 5 | 100% (48–100) | 4 | 80% (28–99) |
| 51–100 | 2 | 2 | 100% (16–100) | 2 | 100% (16–100) |
| > 100 | 2 | 1 | 50% (1–99) | 1 | 50% (1–99) |
Number of samples and sensitivity of uRDT and cRDT stratified by parasite density (p/µL). Diagnostic methods are compared to TBS as reference and all cases were low parasite density samples that occurred during CHMI follow-up