Table III.
Adjusted odds ratio of diagnosis of early stage breast cancer, triple-negative status and treatment by race/ethnicity, age, socioeconomic status and certain tumor characteristics.
| Characteristic | Local stage (95% CI) | Triple-negative (95% CI) | Cancer-directed surgery (95% CI) | Radiation therapy (95% CI) | Chemotherapy (95% CI) |
|---|---|---|---|---|---|
| Race/ethnicity | |||||
| NH white | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| NH black | 0.90 (0.88-0.92)a | 1.78 (1.72-1.83)a | 0.71 (0.68-0.74)a | 0.96 (0.94-0.98)a | 1.12 (1.09-1.15)a |
| NH Asian | 1.09 (1.06-1.12)a | 0.80 (0.77-0.84)a | 0.91 (0.86-0.96)a | 0.84 (0.82-0.86)a | 0.99 (0.96-1.03) |
| Hispanic white | 0.90 (0.88-0.92)a | 1.10 (1.06-1.14)a | 0.92 (0.88-0.97)a | 0.95 (0.93-0.97)a | 1.12 (1.08-1.15)a |
| Hispanic other | 0.82 (0.73-0.93)a | 1.09 (0.93-1.29) | 0.87 (0.70-1.07) | 0.98 (0.88-1.09) | 1.05 (0.93-1.20) |
| Age, years | |||||
| <45 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| 45-54 | 1.15 (1.12-1.18)a | 0.90 (0.87-0.94)a | 0.99 (0.95-1.06) | 1.14 (1.12-1.17)a | 0.62 (0.60-0.64)a |
| 55-64 | 1.29 (1.26-1.32)a | 0.89 (0.86-0.92)a | 0.91 (0.86-0.96)a | 1.33 (1.30-1.37)a | 0.44 (0.42-0.45)a |
| 65-74 | 1.52 (1.48-1.57)a | 0.88 (0.84-0.91)a | 0.82 (0.77-0.86)a | 1.21 (1.18-1.24)a | 0.24 (0.23-0.25)a |
| 75-84 | 1.64 (1.59-1.69)a | 0.86 (0.83-0.90)a | 0.49 (0.47-0.52)a | 0.73 (0.71-0.75)a | 0.06 (0.06-0.07)a |
| ≥85 | 1.81 (1.74-1.89)a | 0.83 (0.78-0.88)a | 0.16 (0.15-0.17)a | 0.25 (0.24-0.26)a | 0.01 (0.01-0.01)a |
| Marital status | |||||
| Married | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Unmarried | 0.97 (0.96-0.99)a | 0.99 (0.96-1.01) | 0.75 (0.73-0.78)a | 0.89 (0.88-0.91)a | 0.86 (0.84-0.87)a |
| Unknown | 1.02 (0.98-1.05) | 1.02 (0.97-1.07) | 0.59 (0.55-0.62)a | 0.75 (0.73-0.77)a | 0.81 (0.78-0.84)a |
| Health insurance | |||||
| Uninsured | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Medicaid | 1.07 (1.00-1.13)a | 0.89 (0.82-0.96)a | 1.69 (1.54-1.84)a | 1.01 (0.95-1.06) | 0.99 (0.93-1.06) |
| Insured | 1.29 (1.21-1.36)a | 0.89 (0.83-0.96)a | 2.56 (2.35-2.79)a | 1.16 (1.10-1.22)a | 1.18 (1.11-1.26)a |
| Unknown | 1.37 (1.27-1.49)a | 0.84 (0.76-0.94)a | 1.13 (1.01-1.26)a | 0.69 (0.64-0.75)a | 0.63 (0.57-0.69)a |
| Household income at | |||||
| county level, $ | |||||
| 19,340-51,269 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| 51,270-58,2549 | 1.02 (0.99-1.05) | 0.96 (0.93-0.99)a | 0.92 (0.88-0.97)a | 1.05 (1.03-1.08)a | 0.94 (0.91-0.97)a |
| 58,250-70,5769 | 1.00 (0.98-1.03) | 0.93 (0.89-0.97)a | 0.86 (0.81-0.90)a | 1.08 (1.06-1.11)a | 0.96 (0.93-0.99)a |
| ≥70,570 | 1.10 (1.07-1.14)a | 0.84 (0.81-0.88)a | 0.76 (0.72-0.80)a | 1.02 (0.99-1.04) | 0.87 (0.84-0.90)a |
| Tumor stage | |||||
| Local | - | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Regional | - | 0.70 (0.68-0.71)a | 0.74 (0.72-0.77)a | 1.40 (1.38-1.43)a | 4.65 (4.56-4.74)a |
| Distant | - | 0.69 (0.66-0.73)a | 0.03 (0.03-0.03)a | 0.66 (0.64-0.68)a | 2.42 (2.33-2.51)a |
| Unknown | - | 0.93 (0.81-1.06) | 0.08 (0.07-0.09)a | 0.36 (0.32-0.41)a | 0.79 (0.71-0.89)a |
| Tumor size, cm | |||||
| <1.0 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| 1.0-1.9 | 0.39 (0.38-0.40)a | 0.95 (0.91-0.98)a | 0.94 (0.89-0.99)a | 0.99 (0.97-1.01) | 1.91 (1.86-1.96)a |
| 2.0-2.9 | 0.18 (0.17-0.18)a | 1.06 (1.02-1.10)a | 0.68 (0.64-0.71)a | 0.78 (0.76-0.80)a | 2.96 (2.88-3.04)a |
| 3.0-3.9 | 0.11 (0.10-0.11)a | 1.23 (1.18-1.29)a | 0.45 (0.43-0.48)a | 0.69 (0.67-0.71)a | 3.65 (3.52-3.77)a |
| ≥4.0 | 0.05 (0.05-0.05)a | 1.29 (1.24-1.34)a | 0.39 (0.37-0.41)a | 0.82 (0.79-0.84)a | 3.73 (3.62-3.85)a |
| Unknown | 0.05 (0.05-0.05)a | 1.28 (1.19-1.36)a | 0.10 (0.09-0.10)a | 0.52 (0.49-0.55)a | 2.49 (2.36-2.63)a |
| Tumor grade | |||||
| Well differentiated | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
| Moderately differentiated | 0.60 (0.59-0.61)a | 4.44 (4.15-4.76)a | 0.93 (0.89-0.97)a | 0.91 (0.89-0.93)a | 2.50 (2.44-2.57)a |
| Poorly/undifferentiated | 0.53 (0.52-0.54)a | 34.65 (32.43-37.02)a | 1.02 (0.98-1.07) | 0.83 (0.82-0.85)a | 9.39 (9.15-9.64)a |
| Unknown | 0.39 (0.37-0.40)a | 12.83 (11.85-13.89)a | 0.28 (0.27-0.30)a | 0.74 (0.72-0.77)a | 3.05 (2.92-3.18)a |
Adjusted for race/ethnicity, age, marital status, insurance, income, tumor stage, size, grade, year of diagnosis and SEER area.
aP<0.05. NH, non-Hispanic.