Table 7.

List of reasons provided by oncologists.

1. The cumulative dose was more important than the single dose. 2. The patient had weakness and lethargy. 3. The dose has been reduced based on the general condition of the patient (height, weight, race, etc.) 4. The patient had low WBC, but it was not registered in his/her paper record. 5. The patient had allergic reactions to a high dose of the drug but did not register in his/her paper record. 6. Drug poisoning occurred in a therapeutic dose. 7. The patient had an infection. 8. The patient had a fever. 9. Because both drugs are hepatotoxic, the physician considers a 1-day interval between the two drugs (IC-BFM 2002). 10. Patients missed appointments. 11. From the doctor’s point of view, starting the drug from the First day of the week was more slightly. 12. Starting the drug from that day leads to more compliance with the protocol (because the duration between doses was more important than delay) 13. The outpatient clinic did not provide any service to patients on weekends.