TABLE A3B.
Regression discontinuity in time (RDiT) design linear model – Spline P‐values when varying discontinuity year
| Spline for 2013 FDA guidance | Spline P‐value |
|---|---|
| March 2007 | .2789 |
| March 2008 | .0716 |
| March 2009 | .0189 |
| March 2010 | .0062 |
| March 2011 | .0024 |
| March 2012 | .0006 |
| March 2013 (base case) | .0003 |
| March 2014 | .0004 |
| March 2015 | .0016 |
| March 2016 | .0094 |
| March 2017 | .0313 |
| Spline for 2018 FDA guidance | Spline P |
| March 2014 | .7516 |
| March 2015 | .6839 |
| March 2016 | .3498 |
| March 2017 | .0951 |
| March 2018 (Base Case) | .0220 |
Abbreviation: FDA, Food and Drug Administration.