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. 2021 Nov 2;42(4):656–666. doi: 10.1177/0271678X211058285

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — (a) Sagittal (upper) and axial (lower) MR(left) and PET images at baseline (center) and following pretreatment with 0.3 mg/kg of JW642 (right). PET images were generated by averaging dynamic scan data at 60–120 min. Arrows in the sagittal PET image under the blocking condition indicate radioactivity accumulations in the choroid plexus. (b, c) TACs for [¹⁸F]T-401 at baseline (b) and following pretreatment with 0.3 mg/kg of JW642 (c). FCX: frontal cortex; STR: striatum; CB: cerebellum; OCC: occipital; HIP: hippocampus; THA: thalamus.