Skip to main content
. Author manuscript; available in PMC: 2022 Mar 24.
Published in final edited form as: Hepatology. 2021 Feb 18;73(3):901–919. doi: 10.1002/hep.31628

Figure 2. NcDase deficiency reduces liver inflammation, fibrosis, and cell death in HSPC-or MCD-fed mice.

Figure 2

WT mice or NcDase−/− mice were fed the HSPC diet (A-F) or MCD diet (G).

(A-C) Masson’s trichrome staining (A), Sirius red staining (B) or H&E staining (C) of liver sections.

(D) Serum ALT levels.

(E) mRNA levels of the indicated genes related to inflammation and fibrosis in liver.

(F) FACS analysis of CD11b+F4/80+ macrophages and CD11b+Gr-1+ iMCs/MDSCs in the liver.

(G) H&E staining (top) or Sirius red (bottom) staining of liver sections in MCD-fed mice.

Mean ± SEM; n = 10, *p < 0.05, **p < 0.01.