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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Biofabrication. 2021 Dec 1;14(1):10.1088/1758-5090/ac3acb. doi: 10.1088/1758-5090/ac3acb

Figure 5: Influence of MEW meshes on MSC chondrogenesis and neocartilage formation.

Figure 5:

(a) Representative images of MSC-laden hydrogels and composites (2 kPa NorHA hydrogel formulation). Hydrogels and composites are cultured in chondrogenic media for up to 56 days and assessed for (b) chondrogenic gene expression (Aggrecan, Type II Collagen), (b) compressive moduli, and (c) biochemical content (DNA, sulfated glycosaminoglycan (sGAG), and collagen (COL)) after 0 (light gray), 7 (dark gray), 28 (blue), and 56 (teal) days of culture in chondrogenic media. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001, n.s. = not significant, n≥3, individual one-way ANOVAs (Aggrecan) or Kruskal–Wallis tests (Type II Collagen) performed for each formulation for qRT-PCR data.