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. 2022 Mar 24;22:316. doi: 10.1186/s12885-022-09377-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 10 — The associations between risk score and immunotherapy. A The expression levels of tumor mutation burden in low-risk group and high-risk group. B The correlation of risk score and tumor mutation burden. C The distribution of microsatellite status in different risk groups. D The risk score in patients with different microsatellite statuses. E-F The abundance of M2 macrophages infiltration and CD8 T cells infiltration in high-risk group and low-risk group. G-H The expression pattern of CD69 and TIM-3 in high-risk group and low-risk group. I-L The relationship between different risk groups and immunophenoscores