Table 4.
List of NCs used in clinics or in clinical trials [200]
| Products | Drug | Nanocarrier | Application |
|---|---|---|---|
| In clinics | |||
| ADI-PEG 20 | Arginine deaminase | Polymeric | Hepatocellular carcinoma |
| Doxil | Doxorubicin | Polymeric | Leukemia, lymphoma, and carcinoma |
| AP5280 | Platinum | Polymeric | Solid tumors |
| DepoCyt | Cytarabine | Liposomal | Lymphomatous meningitis |
| MAG-CPT | Camptothecin | Polymeric | Solid tumors |
| Visudyne | Verteporfin | Liposomal | Macular degeneration |
| Oncaspar | L-Asparaginase | Polymeric | Lymphoblastic leukemia |
| Pegasys | Interferon alfa-2a | Polymeric | Hepatitis B and hepatitis C |
| Clinical trials | |||
| PNU166945 | Paclitaxel | Polymeric | Solid tumors |
| Lipoplatin | Cisplatin | Liposomal | Non-small cell lung cancer |
| XMT-1001 | Camptothecin | Polymeric | Gastric cancer and lung cancer |
| Onco-TCS | Vincristine | Liposomal | Relapsed non-Hodgkin lymphoma |
| OSI-211 | Lurotecan | Liposomal | Head, neck, and ovarian cancer |
| SPI-077 | Cisplatin | Liposomal | Head, lung, and neck cancer |
| PEG-SN38 | Irinotecan derivate | Polymeric | Solid tumors and breast cancer |
| Livatag | Doxorubicin | Polymeric | Liver cancer |
| NKTR-105 | Docetaxel | Polymeric | Solid tumors and ovarian cancer |
| Paclical | Paclitaxel | Polymeric | Breast, lung, and ovarian cancer |
| PEG-docetaxel | Docetaxel | Polymeric | Solid tumors |