Table 1.
Clinical Characteristics of Patients With and Without Asthma
| Characteristic | Asthma (N = 183) |
Non-asthma (N = 1319) |
Pa |
|---|---|---|---|
| Demographics | |||
| Age (y), median (IQR) | 56 (43.0-66.0) | 62.0 (49.0-72.0) | <.001 |
| Female, n (%) | 119 (65) | 547 (41) | <.001 |
| Race, n (%) | .18 | ||
| American Indian/Alaskan native | 0 (0) | 6 (0) | |
| Asian | 4 (2) | 46 (3) | |
| Black | 63 (34) | 327 (25) | |
| Native Hawaiian/other Pacific Islander | 0 (0) | 1 (0) | |
| White | 100 (55) | 810 (61) | |
| Other | 8 (4) | 67 (5) | |
| Unknown | 8 (4) | 62 (5) | |
| Hispanic | 6 (3) | 41 (3) | .90 |
| Outside hospital transfers, n (%) | 37 (20) | 270 (20) | .94 |
| Admit group, n (%) | <.001 | ||
| 1 (March 4-June 14) | 110 (60) | 518 (39) | |
| 2 (June 15-December 31) | 73 (40) | 801 (61) | |
| Comorbid conditions | |||
| Charlson Comorbidity Index, median (IQR) | 3.0 (1.0-5.0) | 2.0 (0.0-5.0) | .002 |
| Comorbid diseases, n (%) | |||
| OSA | 59 (32) | 200 (15) | <.001 |
| COPD | 12 (7) | 104 (8) | .53 |
| Hypertension | 86 (47) | 578 (44) | .42 |
| CAD | 23 (13) | 175 (13) | .79 |
| Diabetes mellitus | 55 (30) | 382 (29) | .76 |
| Obesity | 118 (64) | 631 (48) | <.001 |
| Smoking status, n (%) | .72 | ||
| Current | 4 (2) | 46 (3) | |
| Former | 52 (28) | 402 (30) | |
| Never | 89 (49) | 605 (46) | |
| Unknown | 38 (21) | 266 (20) | |
| Laboratory values at presentation | |||
| White blood cell count (cells/µL), median (IQR) | 7.2 (5.0-10.3) | 7.1 (5.1-10.1) | .95 |
| Ferritin (mg/L), median (IQR)b | 499.3 (192.2-1089.4) | 691.8 (303.5-1366.1) | .001 |
| D-dimer (mcg/ml), median (IQR) | 1.0 (0.6-2.6) | 1.1 (0.6-2.1) | .92 |
| CRP (mg/L), median (IQR) | 8.0 (4.0-14.7) | 7.7(3.8 – 15.7) | .98 |
| Absolute lymphocyte count (cells/µL), median (IQR) | 1.0 (0.6-1.3) | 0.9 (0.6-1.3) | .78 |
Abbreviations: ALC, absolute lymphocyte count; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; IQR, interquartile range; OSA, obstructive sleep apnea.
NOTE. Missing data from non-asthma cohort included 332 without ferritin, 363 without D-dimer, 357 without CRP, and 69 without ALC count.
Note- Bolded p-values are statistically significant using the cut off value of p<.05.
a
P value represents Fisher exact test for categorical variables.
b
Missing data from asthma cohort included 15 without ferritin, 22 without D-dimer, 17 without CRP, 5 without ALC.