Figure 3.

Neural activation during the social gambling task. A, Amygdala activity was significantly enhanced during the decision phase of the social gambling task when participants chose the risky option with a human partner compared with the computer partner (right: 22, −6, −12, t₍₇₃₎ = 4.58, p_FWE = 0.002; left: −22, −8, −12, t₍₇₃₎ = 4.23, p_FWE = 0.006). In line with the behavioral results, no group differences in neural activity were observed during the decision phase. B, During the feedback stage, participants with HL showed attenuated NAcc responses to negative feedback given by human partners compared with the computer partner. In contrast, NAcc reactivity to negative human feedback was enhanced compared with computer feedback in participants with LL. Shaded areas represent the SEM of the fitted responses based on the HRF. For illustration purpose, clusters are shown with significance levels of p < 0.05 uncorrected. L, left; R, right.