Table 1.
Patient and treatment characteristics
| First group | Second group | Salvage | P-value | ||
|---|---|---|---|---|---|
| Patient Number | 20 | 5 | 6 | ||
| Age (mean ± SD) (years) | 62 ± 7.7 | 66 ± 11 | 62 ± 9.7 | 0.68 | |
| Age (years) | (>65: ≤65) | 10: 10 | 4: 1 | 3: 3 | 0.51 |
| Male: Female | 19: 1 | 3: 2 | 5: 1 | 0.07 | |
| WHO PS | (0: 1: 2) | 9: 9: 2 | 3: 1: 1 | 1: 4: 1 | 0.47 |
| Tumor site | (Right: Left) | 7: 13 | 5: 0 | 2: 4 | 0.06 |
| Gross residual tumors (+: -) | 3: 17 | 5: 0 | 4: 2 | < 0.001 | |
| Pathology | |||||
| (Epi: Bip: Sar: unknown) | 13: 7: 0: 0 | 2: 2: 1: 0 | 3: 0: 2: 1 | 0.03 | |
| Asbestos exposure | |||||
| (+: -: unknown) | 11: 5: 4 | 1: 3: 1 | 1: 3: 2 | 0.97 | |
| Stage (1a: 1b: 2: 3a: 3b) | 0: 12: 1: 5: 2 | 1: 3: 0: 0: 1 | 1: 1: 2: 1: 1 | 0.16 | |
| T stage | (1: 2: 3: 4) | 0: 9: 9: 2 | 1: 1: 2: 1 | 1: 0: 4: 1 | 0.37 |
| N stage | (0: 1) | 13: 7 | 5: 0 | 3: 3 | 0.56 |
| Surgery type | (EPP: PD: None) | 20: 0: 0 | 0: 0: 5 | 4: 1: 1 | < 0.001 |
| Chemotherapy | |||||
| (None: Con: Adj: NAC) | 5: 0: 4: 11 | 2: 1: 1: 1 | 0: 0: 3: 3 | 0.17 | |
| Hyperthermia (+: -) | 5: 15 | 1: 4 | 2: 4 | 1 | |
| Irradiated volume | |||||
| (WHI: LSPI: visible tumor only) | 20: 0: 0 | 0: 4: 1 | 4: 1: 1 | < 0.001 | |
Adj: adjuvant, Bip: biphasic, Con: concurrent chemotherapy, Epi: epithelioid, NAC: neo-adjuvant chemotherapy, LSPI: lung sparing pleural irradiation, PS: performance status, PD: pleurectomy/decortication, Sar: sarcomatoid, SD: standard deviation, WHI: whole hemithorax irradiation.