Table 2.
Radiotherapy details
| WHI | LSPI | P-value | ||
|---|---|---|---|---|
| Patient Number (Mean ± SD) | 24 | 5 | ||
| PTV(cc) | 3583 ± 1141 | 2640 ± 1037 | 0.1 | |
| Prescription dose (Gy) (median, range) | 50.4 (45–60) | 45 (45–60) | 0.71 | |
| Fraction number (median, range) | 28 (25–33) | 15 (15–30) | 0.1 | |
| Conformity Index | 1.96 ± 0.95 | 2.62 ± 1.09 | 0.18 | |
| Uniformity index | 1.08 ± 0.05 | 1.37 ± 0.18 | < 0.001 | |
| CTV covered | ||||
| Surgical tract (+: -) | 7: 17 | 2: 3 | 0.46 | |
| Mediastinal region (+: -) | 11: 13 | 3: 2 | 0.32 | |
| Tumor side (right: left) | 7: 17 | 5: 0 | 0.001 | |
| Virtual block (+: -) | 4: 20 | 1: 4 | 1 | |
| Mean lung dose (Gy) | 6.1 ± 3.1 | 18.4 ± 2.8 | < 0.001 | |
| Mean heart dose (Gy) | 29.5 ± 8.5 | 25.4 ± 4.4 | 0.64 | |
| Spinal cord maximum dose (Gy) | 29.5 ± 2.4 | 39.3 ± 4.5 | 0.15 | |
| Esophagus maximum dose (Gy) | 53.4 ± 1.5 | 45.6 ± 3.7 | 0.27 | |
| Stomach maximum dose (Gy) | 50.1 ± 3.0 | 30.2 ± 2.1 | 0.02 | |
LSPI: lung sparing pleural irradiation, PTV: planning target volume, SD: standard deviation.
WHI: whole hemithorax irradiation.
The UI and mean lung dose were significantly higher in LSPI plans (P < 0.001).