Table 1.
Relationship between GGCT expression and clinicopathological characteristics in 178 PTC tissues
| Clinicopathologic parameters | n | GGCT expression | P | |
|---|---|---|---|---|
| low | high | |||
| All cases | 178 (100%) | 67 (37.6%) | 111 (62.4%) | |
| Age, y | 0.848 | |||
| ≤55 | 60 (33.7%) | 22 (36.7%) | 38 (63.3%) | |
| >55 | 118 (66.3%) | 45 (38.1%) | 73 (61.9%) | |
| Gender | 0.159 | |||
| male | 69 (38.8%) | 20 (29.0%) | 49 (71.0%) | |
| female | 119 (61.2%) | 47 (39.5%) | 72 (60.5%) | |
| Histological type | <0.001 | |||
| classical | 106 (59.6%) | 39 (36.8%) | 67 (63.2%) | |
| follicular | 28 (15.7%) | 19 (67.9%) | 9 (32.1%) | |
| tall cell | 44 (24.7%) | 9 (20.5%) | 35 (79.5%) | |
| Multifocality | 0.218 | |||
| unifocal | 129 (72.5%) | 45 (34.9%) | 84 (65.1%) | |
| multifocal | 49 (27.5%) | 22 (44.9%) | 27 (55.1%) | |
| Extrathyroidal extension | 0.035 | |||
| no | 133 (74.8%) | 56 (42.1%) | 77 (57.9%) | |
| yes | 45 (25.2%) | 11 (24.4%) | 34 (75.6%) | |
| T classification | 0.004 | |||
| T1-T2 | 117 (65.8%) | 53 (45.3%) | 64 (54.7%) | |
| T3-T4 | 61 (34.2%) | 14 (23.0%) | 47 (77.0%) | |
| Lymph node metastasis | 0.395 | |||
| no | 87 (48.9%) | 30 (34.5%) | 57 (65.5%) | |
| yes | 91 (51.1%) | 37 (40.7%) | 54 (59.3%) | |
| TNM stage | 0.002 | |||
| I + II | 128 (71.9%) | 57 (44.5%) | 71 (55.5%) | |
| III + IV | 50 (28.1%) | 10 (20.0%) | 40 (80.0%) | |
| Braf-V600E mutation | 0.975 | |||
| no | 72 (40.4%) | 27 (37.5%) | 45 (62.5%) | |
| yes | 106 (59.6%) | 40 (37.7%) | 66 (62.3%) |