Fig. 1.

The DNA damage of lung tissue cells at the acute phase after treatments. (A) Representative confocal images show the expression of Sca-1 and γ-H2AX in lung tissue cells. Quantitative data on the number of Sca-1⁺ stem cells (B), the total cells with γ-H2AX foci formation (C), and the Sca-1⁺ stem cells with γ-H2AX foci formation (D, Arrows) are shown. Scale bars: 10 μm. The nuclei were stained with DAPI. Data are represented as means ± SD. **p < 0.01 vs CON group, †p < 0.05, ††p < 0.01 vs IR group. CON: Control, IR: Radiation, IR + N: Radiation+Nicaraven.