Skip to main content
. 2022 Mar 2;11(1):18. doi: 10.3390/antib11010018

Table 8.

Evolving HLA-EG mAbs: HLA-F and HLA-G non-reactive but reactive to HLA-A, HLA-B, and HLA-C alleles.

Groups G-VII
MFI Expressed in Thousands
Subgroups [A] [B] [C] [D] [E] [F] [G]
Number of mAbs 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
mAb Nomenclature TFL-221 TFL-218 TFL-217 TFL-216 TFL-196 TFL-167 TFL-231 TFL-252 TFL-170 TFL-169 TFL-166 TFL-168 TFL-251 TFL-207 TFL-206 TFL-205 TFL-243 TFL-246 TFL-244 TFL-245 TFL-189 TFL-190 TFL-188 TFL-172 TFL-171
IgG Subclass NT IgG1 IgG1 IgG1 IgG2a IgG1 IgG2b IgG2b IgG1 IgG1 IgG1 IgG1 IgG2b IgG1 IgG1 IgG1 IgG2a IgG2a IgG2a IgG2a IgG1 IgG1 IgG1 IgG1 IgG1
HLA-ER Reactivity 25 21 20 20 24 24+ 25 26 18+ 19 26 24+ 25 25 13+ 14+ 14
HLA-EG Reactivity 25 20 19+ 20 24 15 24 25 17 17+ 16+ 15 25+ 17+ 19 18+ 25 24+ 24+ 24+ 15+ 16+ 16 14+ 15
HLA-F Reactivity
HLA-G Reactivity
HLA-A Reactivity A*0101 14 15
A*0201 1 1
A*0203 1+ 1+
A*0206 1 1 1 1 1 1 1 1 1+ 1+ 1+
A*0301 12+ 14
A*1101 6 5 5+ 5+ 4 5+ 8+ 9+ 6+ 6+ 6+ 6+ 9+ 8 8 8 12 12 12 12 1+ 1+ 1+ 9+ 10
A*1102 11 10+ 11+ 11 11 11+
A*2402 1 1 1 1 1 1+ 2+ 3 2 2 2 2 3 3 3 3 2+ 2+ 3 3 1 1
A*2403 1 1 1 1 1 1 1 1+ 1+ 1+
A*2601 1 1+ 2 1+ 2 2 2 2 2+ 3 3 3 1 1
A*2901 1 1 1+ 1+ 1+ 1+ 1+ 1+ 2 2 2
A*3001 1 1 1 1 1 1 1+ 1+ 1+
A*3002 1 1 1 1 1 1 1 1+ 2 2 2
A*3201 1 1 1 1 1 1 1 1+ 1+ 1+ 1+
A*3301 1 1 1 1 1 1 1 1+ 1+ 1+
A*3303 1 1 1+ 1+ 1+ 1+ 1+ 1+ 2 2 2 14+ 15
A*3401 1 1 1 1 11 12
A*3402 1 1 1 11+ 12
A*3601 1 1 1 1 1 1+ 1+ 1+ 11 12
A*4301 1 1 1 11+ 12+
A*7401 1+ 1+ 1 1 1 1+ 1+ 1+ 1+ 1+ 2 2+ 13+ 14
A*8001 3 3+
HLA-B Reactivity B*0702 1 1 1
B*0801 15+ 3 3 3 1+ 2+ 23 4 3 3 3 3 4 20+ 19 20 1+ 1+ 1+ 1+ 11 11+
B*1301 16+ 17 17+ 17+ 2 4 24 6 4+ 4+ 4+ 4+ 6 20+ 19+ 20 3 3 3 3 <1 1 1 2 2+
B*1302 3 3 3 3 2 3+ 6 6+ 4+ 4+ 4+ 4+ 7 6 6 6 8 9 8 8+ <1 <1 1 2 2+
B*1401 1 1+ 1 1 1 1 1+ 2 2 2 7+ 7 7+ 8
B*1402 4 7+ 8 8+ 11 12+ 12+ 12+
B*1501 10+ 12+ 12+ 13 1 2 17+ 3+ 2+ 2+ 2+ 3 3+ 16+ 16+ 16+ 6 6 6 6+ 1 1
B*1502 1 1 1 1 1 1 1+ 1+ 1+ 15+ 15 15+ 15+ 12 13
B*1503 1 1 1 1+ 1+ 1+ 10 9+ 10 10+
B*1510 1+ 4 4+ 5 5+ 8 7+ 8 1+ 1+
B*1511 10+ 8+ 9 8+ 6+ 8 13+ 14 9 9 9 9 14 11+ 10+ 11 10+ 10+ 10 10 4 4+ 4+ 11+ 12
B*1512 17+ 17+ 17+ 18 1 2+ 23+ 3+ 3 3 3 3 3+ 20 20 19+ 8+ 7+ 8+ 9 1 1
B*1513 12+ 15+ 16+ 17 1 22 1 1 1 1 1 1 20 18+ 19 7+ 7 8 8+ 14+ 15+
B*1516 1+ 1+ 1+ 1+ 1 2 3 3+ 2+ 2+ 2+ 2+ 3+ 3+ 3+ 3+ 1 1+ 1+ 1+ 1 1
B*1801 1 1
B*2705 1 1 1 1
B*2708 1 1 1+ 1+ 1 2 2+ 3+ 2+ 2+ 2+ 2+ 3+ 3+ 3 3+ 1 1 1 1 1
B*3501 1 1+ 1+ 1+ 1 2 3+ 4 3 2+ 3 3 4 4 4 4 1+ 1 1+ 1+ 13 14+
B*3701 0 0 0 0 1 1 1
B*3901 2+ 2 2+ 2+ 1+ 3 4+ 5+ 3+ 3+ 3+ 3+ 5+ 5 5 5 2+ 2+ 2+ 2+ 11 12+
B*4001 1 1 1 1 1+ 2 2+ 2 2 2 2 2+ 3 3 3 1 1 1 1 7 7+
B*4002 2 1+ 2 2 1+ 2+ 4 5+ 3+ 3 3+ 3+ 5 4+ 4+ 4+ 2+ 2+ 2+ 2+ 9 9+
B*4006 1 1 1+ 1+ 1+ 1+ 1+ 1+ 2 2 2
B*4201 1+ 1 1+ 1+ 1 2 3 4 2+ 2+ 2+ 2+ 4 4 4 4 3 2+ 3 3 12+ 13+
B*4402 2+ 2 2 2 1+ 3 4+ 5+ 3+ 3+ 3+ 3+ 5+ 5 5 4+ 2+ 2+ 2+ 2+ 8+ 9
B*4403 0 0 0 0 1 1 1 1 1 1 1+ 1+ 1+ 6 6
B*4501 16+ 18 18+ 18+ 1+ 23+ 2 2 1+ 2 2 2 20 20 20+ 13+ 15
B*4601 1 1 1+ 1 1 1 1 1+ 2 2 2 10+ 11+
B*4701 1 1 1 1 1 1 1 1+ 1+ 1+ 12 14
B*4801 3+ 2+ 3+ 4 9 9+
B*4901 4+ 4 5 5 8+ 9+
B*5001 1 1+ 1+ 1+ 1 2 3+ 4 2+ 2+ 2+ 2+ 4 4 4 4 6+ 5+ 6+ 7 1 1
B*5101 1 1 1+ 1 1 1 1 1+ 2 2 2 5 4 5 5+
B*5102 1 1 1 1 1 1 1+ 1+ 1+ 2 3+ 3 4 4 11 12
B*5201 7 6 6+ 6+ 4+ 6+ 10+ 11 7+ 7+ 7 7+ 11 9+ 9+ 9+ 6+ 7 6+ 7 2 2+ 2+ 4+ 5
B*5301 1 1 1+ 1+ 1 2 2 3+ 2+ 2+ 2+ 2+ 3+ 3 3 3 1 1 1 1+ 1 1
B*5401 1 1 1 1 1 1+ 2+ 3+ 2 2 2 2 3+ 3 3 3+ 15+ 15+ 15 15 1 1
B*5501 9+ 1 1 1+ 1 1 1 1 1+ 1+ 1+ 1+ 0 0 0 0
B*5601 7 9 9+ 15 1 1+ 12+ 2+ 2+ 2 2+ 2+ 3 13 12+ 12+ <1 1 1 1 2 2
B*5701 13 14+ 14+ 6+ 1 2+ 20 4 3 3 3 3 4 17+ 17+ 18 1 1 1 1 4+ 5
B*5703 7+ 6+ 6+ 2 4+ 6 10+ 10+ 7 7 7 7 10+ 9 8 9 7 7 6+ 7 2+ 3 2+ 7 7+
B*5801 1+ 1+ 2 1 1 2+ 4 4+ 3 3 3 3 4+ 4+ 4+ 1+ 1+ 1+ 1+ 2+ 3 3 1 1+
B*6701 1 1 1 1+ 1 1+ 2 2+ 2 2 2 2 2+ 3 3 3 1
B*7301 1 1+ 2+ 1+ 1+ 1+ 1+ 2+ 2+ 2+ 2+ 12+ 12 12 13
B*7801 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0
B*8101 1 1 1+ 0 1 2 3 4 2+ 2+ 2+ 2+ 4 3+ 3+ 3+ 1+ 1+ 1+ 1+ 1 1
B*8201 1 1 2 1+ 1+ 1+ 1+ 2+ 2 2 2 12 13 13 14 16
HLA-C Reactivity C*0102 1 1 1 1 1 1 1+ 1+ 1+ 1+ 10+ 11+ 11+ 14 15+
C*0202 1+ 1 2+ 1+ 1+ 1+ 1+ 2+ 2+ 2+ 2+ 13+ 11+ 13+ 13+ 13+ 13+ 14+ 13+ 15
C*0302 1 1 1 1 1 1 1+ 1+ 1+ 8 6+ 8+ 8 16+ 16+ 16+ 14 15+
C*0303 1 1 1 6 1 2 2 3+ 2+ 2+ 2+ 2+ 3+ 3+ 3 3+ 9 7+ 9 9 15 15 15 14 15+
C*0304 1 1 2 1+ 1+ 1+ 1+ 2 2 2 2 5+ 6+ 6+ 13+ 15
C*0401 6+ 5+ 6 5+ 4+ 6 9 10+ 7 7 6+ 7 10+ 8+ 8+ 8 6+ 6+ 6+ 6+ 10 11+ 11 13 14
C*0501 1 1 2 1+ 1+ 1+ 1+ 2 2 1+ 2 1 1 1 1 20 20 19 13 14+
C*0602 1 1 1+ 1 1 1 1 1+ 1+ 1+ 1+ 11+ 10 12 12 17+ 17+ 18 12 14
C*0702 5+ 5+ 5+ 1 9+ 6+ 6+ 6+ 6+ 9+ 8 7+ 7+ 5+ 5+ 5+ 5+ 11 12+ 12+ 13+ 15
C*0801 1 1 1 1 1 1 1+ 1 1 20 20+ 20 15+ 17
C*1203 1 1 2 1 1+ 1+ 3 2 2 2 2 3 2+ 2+ 2+ 1 1 1 1 13 13+ 14 13+ 14+
C*1402 1+ 1+ 2 7+ 1+ 2+ 3+ 4+ 3 3 3 3 4+ 4 3+ 4 19+ 19+ 19+ 19+ 18+ 18+ 18 14+ 16
C*1502 1 1 2 1 1 1 1 2 2 1+ 2 24+ 24+ 24+ 24+ 18+ 19 18+ 13+ 15
C*1601 1 1 11 2 1+ 1+ 1+ 1+ 2+ 2+ 2+ 2+ 22 21+ 21+ 21+ 16 16+ 17 13 14+
C*1701 8+ 7 7+ 4+ 5 7 24+ 12 8 8 8 8 12 10 9+ 9+ 8 8 8 8 11+ 12+ 12+ 14+ 16
C*1802 18 4+ 4+ 0 1+ 3+ 5+ 4 4 4 4+ 6 20+ 20 20+ 2+ 2+ 2+ 2+ 1 1 1 13 14+