The metabolism of cysteine and related thiol compounds in mammals. ADP, adenosine diphosphate; AMP, adenosine monophosphate; ATP, adenosine triphosphate; CDP, cytidine diphosphate; CTP, cytidine triphosphate; ENPP1, ectonucleotide pyrophosphatase/phosphodiesterase 1; GSH, glutathione; GSSG, glutathione disulfide; NAD+, nicotinamide adenine dinucleotide; NADH, nicotinamide adenine dinucleotide hydrogen; NADP+, nicotinamide adenine dinucleotide phosphate; NADPH, nicotinamide adenine dinucleotide phosphate hydrogen; Pi, inorganic phosphate; PPi, inorganic pyrophosphate; Q, substrates or reactants for glutathionylation; THF, tetrahydrofolate; X, substrates for methylation.