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. 2022 Mar 5;11(3):506. doi: 10.3390/antiox11030506

Table 1.

In vitro studies of nanoencapsulation of anthocyanins (polysaccharides, proteins, and lipid-based) for different purposes.

Source Nanoencapsulant Nanoencapsulation Technique Average Size (nm) Purpose Reference
Commercial anthocyanin-rich extract Whey Protein Isolate and Pectin Thermal processing and electrostatic complexation 200 Increase antioxidant capacity [166]
Red cabbage Palmitic acid and surfactants Emulsion 455 Stability and antioxidant capacity [199]
Black rice bran Chitosan and Alginate Ionic pre-gelation and polyelectrolyte complex 219.53 Stability [170]
Blueberry Carboxymethyl Chitosan Self-assembly 219.53 Protection and stability [171]
Açai berry Eudragit® L100 Modified double-emulsion solvent extraction/evaporation 570–620 Safety [173]
Blueberry Chitosan Hydrochloride, Carboxymethyl Chitosan Electrostatic interaction 178.1 Stability and bioavailability [169]
Blueberry Whey Protein, Polyglycerol Polyricinoleate Nanoemulsion ˂400 Protection and stability [185]
Natural Source
Plant
Lecithin and Cholesterol Nanoliposomal 53.01 Stability and bioavailability [186]
Blueberry Chitosan Hydrochloride, Carboxymethyl Chitosan, and β-Lactoglobulin Electrostatic interaction 91.71 Stability and bioavailability [168]
Black rice Chitosan/Chondroitin sulfate Self-assembly 350.1 Antioxidant capacity [200]
Red raspberry pomace β-Lactoglobulin Desolvation 129.13–351.85 Stability and bioavailability [1]
Bilberry Chitosan and Pectin Self-assembly 100–300 Stability and bioavailability [172]
Black carrot Chitosan Ionic gelation 274 Increase antioxidant capacity [201]
Blackberry
Commercial anthocyanin-rich extract
Pectin and Lysozyme
Casein and Carboxymethyl Cellulose
Self-assembly
Self-assembly
198.5
209.9
Protection and stability
Stability
[164]
[202]