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Autoradiography and Oil Red O staining of en face aortic arches demonstrate the specific binding of [89Zr]Zr-anti-CD40 mAb to plaque areas. (A) Autoradiography and Oil red O staining in both an ApoE−/− and WT mouse. Arrows indicate plaque regions. (B) Quantification of autoradiography intensity in all groups. * p < 0.05; WT N = 3, ApoE−/− “low dose” N = 5, ApoE−/− “high dose” N = 6.
