Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 8;10(3):626. doi: 10.3390/biomedicines10030626

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The result of thee semisolid agar colony-forming assay. Anchorage-independent growth in soft agar was examined with control cells and cells that displayed downregulation of SMOX expression. The numbers of colonies were measured after 14 days. Colony formation in the siRNA-treated group was reduced compared to that in the control group (HCT116, 31%; HT29, 38%; SW480, 33%; and SW620, 21%). Colonies were visualized in violet color. (A) Comparison of the growth of colonies with control cells and siRNA-treated cells (Original magnification ×40). (B) The graph indicates the number of colonies and the percentage difference between the control cells and siRNA-treated cells (* p < 0.05, *** p < 0.001).