Å	angstrom (unit of length equal to 10−10 m)
aa	amino acid
AC8	adenylyl cyclase 8
AKAP	A-kinase anchoring protein
ARF6	adenosine diphosphate ribosylation factor 6
BiFC	bimolecular fluorescence complementation
Ca2+	calcium ion
CAD	Ca2+ release-activated Ca2+ activating domain
CaM	calmodulin
CaMMUT	calmodulin mutant
cAMP	cyclic adenosine monophosphate
Cav-1	Caveolin-1
CB	cholesterol-binding
CC	coiled-coil
Ccb9	coiled-coil domain containing region b9
CDS	CDP-diacylglycerol synthase
CRAC	Ca2+ release-activated Ca2+
cryo-ET	cryo-electron tomography
CTID	COOH-terminal inhibitory domain
DAG	diacylglycerol
DGK	diacylglycerol kinase
EM	electron microscopy
ER	endoplasmic reticulum
ERK	extracellular signaling-related kinase
ETON	extended transmembrane Orai1 N-terminal
FP	fluorescent proteins
GoF	gain of function
GTP	guanosine triphosphate
HEK	human embryonic kidney
hNPCs	human neurons and human neural progenitor cells
IL-2	interleukin-2
IP3	inositol-triphosphate
IP3R	inositol-triphosphate receptor
K+	potassium ion
Kir	inward-rectifier potassium channels
Kv	voltage-gated K+
LoF	loss of function
MßCD	methyl-β-cyclodextrin
MCS	membrane contact site
MD simulations	molecular dynamics simulations
MscL	large-conductance mechanosensitive channel
Na+	sodium ion
NFAT	nuclear factor of activated T-cells
Nir	PYK2 N-terminal domain-interacting
NMR	nuclear magnetic resonance
OASF	Orai-activating small fragment
ORP	oxysterol-binding proteins
PA	phosphatic acid
PALM	photoactivated localization microscopy
PC	phosphatidylcholine
PE	phosphatidylethanolamine
PI4K	phosphoinositide 4-kinases
PIP2	phosphatidylinositol 4,5-bisphosphate
PKC	protein kinase C
PI	phosphatidylinositol
PIs	phosphoinositides
PIS	PI synthase
PIP5K	phosphatidylinositol-4-phosphate-5-kinase
PLC	phospholipase C
PM	plasma membrane
PMCA	plasma membrane Ca2+ pump
PS	phosphatidylserine
PITP	phosphatidylinositol transfer protein
RAS	(RA) association region
RBL	rat basophilic leukemia
SARAF	store-operated calcium entry-associated regulatory factor
SARAH	Salvador-RASSF-Hippo domain
SCID	severe combined immune deficiency
SERCA	sarcoplasmic/endoplasmic reticulum calcium ATPase
SigmaR1	Sigma non-opioid intracellular receptor 1
SK channels	small-conductance Ca(2+)-activated K(+) channels
SM	sphingomyelin
SMase	sphingomyelinase
SOAP	STIM-Orai association pocket
SOAR	STIM-Orai activating region
SOC	store-operated channel
SOCE	store-operated calcium entry
STED	stimulated emission depletion microscopy
STIM	stromal interaction molecule
STIMATE	STIM-activating enhancer
STORM	STochastic optical reconstruction microscopy
TIRFM	total internal reflection microscopy
TM	transmembrane helices
TcB1/2/2	tricarbins
Tyr	tyrosine