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. 2022 Feb 24;10(3):531. doi: 10.3390/biomedicines10030531

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) DNA histograms of monotherapy and combination therapy on HCT116 cell cycle profile. The first and second peaks represent DNA content in G0/G1 and G2/M phases. Cell number plotted against the intensity of PI. Flow cytometric histograms are representative of 3 separate experiments. (B) Cell distribution percentage in each phase of HCT116 cell cycle. Data are presented as mean ± SD of 3 separate experiments, * p < 0.05, ** p < 0.01 indicate significant difference compared to control.

(A) DNA histograms of monotherapy and combination therapy on HCT116 cell cycle profile. The first and second peaks represent DNA content in G0/G1 and G2/M phases. Cell number plotted against the intensity of PI. Flow cytometric histograms are representative of 3 separate experiments. (B) Cell distribution percentage in each phase of HCT116 cell cycle. Data are presented as mean ± SD of 3 separate experiments, * p < 0.05, ** p < 0.01 indicate significant difference compared to control.