Table 5.
A summary of the IC50 values, luminescent properties, and special features of osmium complexes: tridentate terpyridine complex OS2 [105], half-sandwich osmium(II) complex OS3 [106], and, panchromatic osmium(IV) complex OS4 [107].
| Os Complex |
IC50 (μM) | Luminescence | Special Features | ||
|---|---|---|---|---|---|
| Dark (Cell Line) | Light (Irradiation nm) | λEm(max) (nm) |
λEx(max) (nm) |
||
| OS2 | >100 (Hep-G2) | 1.23 ± 0.12 (465) 4.05 ± 0.05 (633) |
~570–770 | 488 | Exhibited high phototoxicities against cancer cells upon both 465 and 633 nm light irradiation. |
| OS3 | 1.1 ± 0.2(A549) | Selective generation of oxidative stress in cancer cells over noncancerous cells. | |||
| OS4 | 550 ± 49 (U87) | 45 ± 5 (NIR) | 940 | 200–900 | These photosensitizers were panchromatic (i.e., black absorbers), activatable from 200 to 900 nm. |