Skip to main content
. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: IEEE Trans Biomed Eng. 2022 Mar 18;69(4):1481–1490. doi: 10.1109/TBME.2021.3120919

Fig. 5.

Fig. 5.

In vivo BBB opening and PCI. Raw contrast enhanced T1-weighted MRI (top panel) for (A) NHP skull and (B) human skull fragments. Thresholded regions of contrast enhancement used for ROC analysis with PCI (middle panel). Overlaid −6 dB focal regions of PCI (bottom panel) for (A) NHP skull and (B) human skull fragments. (C) Representative receiver operator characteristic (ROC) curves demonstrating correlation between contrast-enhanced regions of T1-weighted MRI and −6 dB focal regions of PCI. (D) Area under the curve (AUC) for n=4 mice per group. Error bars denote the mean ± standard deviation.