Skip to main content
. 2022 Mar 3;10(3):602. doi: 10.3390/biomedicines10030602
ALDH2 aldehyde dehydrogenase
AMP adenosine monophosphate
AMPK adenosine monophosphate activated protein kinase
ANGII angiotensin II
AO antioxidant
AOx vitamin C, vitamin E, α-lipoic acid (antioxidants)
AT1R angiotensin II receptor
ATP adenosine triphosphate
BH4 dihydrobiopterin-4
BNIP3 mitochondrial mitophagy marker
BNP brain natriuretic peptide
Bax bcl-2-like protein 4
CAT chloramphenicol acetyltransferase
CHF– chronic heart failure
CI ETC complex I
CIII ETC complex III
CK creatine kinase
CRP– C-reactive protein
Cluh clustered mitochondria protein homolog
CoenzymeQ-10– ubiquinone
DM– diabetes mellitus
DROM reactive oxidative metabolites
DRP1 dynamin related protein1
ERK extracellular signal-regulated kinase
ERK1/2 extracellular signal-regulated kinase 1/2
ETC electron transport chain
GTP guanosine triphosphate
GMP guanosine monophosphate
GPX glutathione peroxidase
GSH glutathione
H2O2 hydrogen peroxide
HF heart failure
HFpEF heart failure with preserved ejection fraction
HFrEF heart failure with reduced ejection fraction
HNO nytroxyl
HSC hematopoietic stem cells
IDH isocitrate dehydrogenase
IDH2 isocitrate dehydrogenase
IL-10 interleukin-10
IL-6 interleukin-6
IMM inner mitochondrial membrane
IRE1α inositol-requiring protein 1α
ISDN isosorbide dinitrate
JNK-c Jun N-terminal kinase
KFP Kaempherol
LA left atrium
LKB1 liver kinase B1
LPHs lipid hydroperoxide
LV left ventricle
LVEDV left ventricle end-diastolic volume
LVESV left ventricle end-systolic volume
LVH left ventricular hypertrophy
LVID left ventricular internal dimension
MAO monoamine oxidase
MAO-A monoamine oxidase A
MAPK mitogen-activated protein kinase
MCU mitochondrial calcium uniporter
MMPs matrix metalloproteinase
NAPDH- nicotinamide adenine dinucleotide phosphate
NFκB nuclear factor kappa-B
NHE-1 Na+/Ca2+ exchanger
NO nitric oxide
NO-2 plasma nitrite
NOS nitric oxide synthase
NOX nicotinamide adenine dinucleotide phosphate oxidase
NP natriuretic peptide
NT-proBNP N-terminal pro b-type natriuretic peptide
NYHA- New York Heart Association
OMM outer mitochondrial membrane
ONOO peroxynitrite
OPA1 optic atrophy 1
P38 a focal point of interactions of the serine/threonine kinases
PDE phosphodiesterases
PKA protein kinase A
PKB protein kinase B
PKC protein kinase C
PKG protein kinase G
PKS protein kinase S
PRR pathogen recognition receptor
PRX peroxiredoxin
RAAS renin-angiotensin-aldosterone system
ROS reactive oxygen species
Rac-1 GTP-binding protein
SGLT2 sodium-glucose cotransporter
SIRT NAD+ dependent class III histone deacetylases
SOD superoxide dismutase
TGFβ tumor growth factor β
TNF-α tumor necrosis factor-α
TPP triphenylphosphonium cation
TXNIP thioredoxin-interacting protein
UCP2 uncoupling protein 2
VDAC1 voltage-dependent anion channel 1
XBP1s X-box-binding protein1
XO xanthine oxidase
XOR xanthine oxidoreductase
cAMP cyclic adenosine monophosphate
cGMP cyclic guanosine monophosphate
eNOS endothelial nitric oxide synthase
hs-CRP high-sensitivity C-reactive protein
iNOS inducible nitric oxide synthase
nNOS neuronal nitric oxide synthase
pGC particulate guanylyl cyclase
sGC soluble guanylate cyclase
β-OX beta-oxidation