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. 2022 Feb 23;10(3):529. doi: 10.3390/biomedicines10030529

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Clustergram graph: LncRNAs expression in obese in comparison with the mean expression in normal-weight adolescents. Red square: up-regulation, green square: down-regulation, black square: no regulation; black crossed square: absence of expression. Panel 1 reports 42 LncRNA and Panel 2 the remaining 45 LncRNAs for a total of 86 LncRNAs that were analyzed. (B) Clustergram of the four selected inflammatory LncRNAs (LINC00657, RP11-10K16.1, RP11-347E10.2, and SNHG12). On the columns the acronyms of the obese and normal-weight subjects, on the lines the names of the LncRNAs; green represents down-regulation, red represents up-regulation. (C) Dynamic heat-map graph of LINC00657, RP11-10K16.1, RP11-347E10.2, and SNHG12 in the obese and control group. On the column are the number of obese and normal-weight samples. Red square: down-regulation, blue square: up-regulation.