Table 1. Cell Surface Markers Differentially Expressed in ANPhigh and ANPlow PMNa.
| saline | LPS | |
|---|---|---|
| Gene | logFC (ANPlow/ANPhigh) | logFC (ANPlow/ANPhigh) |
| Tnfrsf26 | –1.73262421 | –2.657676 |
| Clec7a | –1.044724054 | –2.078300 |
| Cd244 | –0.816499782 | –1.970690 |
| Cxcr3 | –1.621891364 | –1.621890 |
| Tnfrsf8 | –0.963506698 | –1.577790 |
| Il15ra | –0.048885223 | –1.420680 |
| Pecam1 | –0.272222647 | –1.358090 |
| Cd274 (PD-L1) | –1.328938411 | –1.357850 |
| Tlr6 | –0.805369715 | –1.287680 |
| Cd68 | –0.878052769 | –1.211180 |
| Tnfrsf9 | –0.498199032 | –1.205280 |
| Procr (CD201) | –0.099146427 | –1.199040 |
| Cd40 | –0.544657965 | –1.161850 |
| Cxcr4 | –0.919071003 | –1.158270 |
| Tlr1 | –0.37362063 | –1.116150 |
| Ccrl2 | –1.527591012 | –1.089050 |
| Cd3e | –0.069573722 | –0.978163 |
| Cd74 | –0.608901968 | –0.958716 |
| Jaml | 0.026618296 | –0.945136 |
| Itgax (CD11c) | –0.800173707 | –0.928278 |
| Cd84 | –0.193804427 | –0.846793 |
| Cd115 | –0.505175069 | –0.763241 |
| Ccr1 | –0.232941656 | –0.732656 |
| Klrb1 (NK1.1) | 0.492338778 | –0.682963 |
| Itgb7 | –0.417413035 | –0.649137 |
| Ccr7 | –0.24938707 | –0.629915 |
| Sell (CD62L) | 0.119925807 | –0.529186 |
| Icam1 | –1.075309125 | –0.314039 |
| Thy1 | –0.095529324 | –0.271720 |
| Ptprc (B220) | –0.458431681 | –0.156455 |
| Fcgr3 (CD16) | 0.257091771 | –0.119756 |
| Cxcr2 | 0.555029693 | 0.449032 |
| Itgam (CD11b) | 0.298204347 | 0.693555 |
| Ly6g | 1.884798818 | 1.081058 |
| Cd177 | 1.610499768 | 1.148760 |
| Cd81 | 0.110210089 | 1.395810 |
| Nt5e (CD73) | 1.175626193 | 1.436910 |
| Cd55 | 0.840994987 | 1.656220 |
a
logFC (ANPlow/ANPhigh) of mRNA expression of 38 genes encoding cell surface markers. Canonical marker of leukocyte subtypes in bold. Names of recognized epitopes in brackets. Mice were injected with LPS or saline 6 h prior to euthanasia and with AF647-fluorochrome labeled ANP 30 min prior to euthanasia. Lung Ly6G+ PMN were sorted according to ANP-endocytosis and their mRNA was processed for RNA-Seq.