Table 1.
KEGG pathway enrichment results of regulatory enzymes.
| Enrichment Pathway | Observed Gene Count | Background Gene Count | Matching Proteins in Our Network |
|---|---|---|---|
| Histidine metabolism | 5 | 16 | ALDH3A1, ALDH1A3, DDC, ABP1, HRH2 |
| Valine, leucine and isoleucine biosynthesis | 3 | 8 | BCAT1, BCAT2, IARS, LARS2 |
| Aminoacyl-tRNA biosynthesis | 5 | 48 | CCBL1, GMPS, TGM3, BCAT1, BCAT2 |
| D-Glutamine and D-glutamate metabolism | 2 | 6 | CCBL1, GMPS, TGM3 |
| Neomycin, kanamycin and gentamicin biosynthesis | 1 | 2 | GCK, HK3, SI |
| Arginine biosynthesis | 2 | 14 | GLS2, GLS |
| Glycine, serine and threonine metabolism | 3 | 33 | MAOB, MAOA, CEL, GAMT, GATM |
| Pentose and glucuronate interconversions | 2 | 18 | TKTL1, RPE, TKTL2 |
| Pyrimidine metabolism | 3 | 39 | NT5C1A, NT5C, NT5M |
| Purine metabolism | 4 | 65 | XDH, HPRT1, PNP, APRT, HPRT1, GDA |
| Pentose phosphate pathway | 2 | 22 | PGM1, PGM2, PNP, UPP1 |
| Nitrogen metabolism | 1 | 6 | CCBL1, GMPS, TGM3 |
| Galactose metabolism | 2 | 27 | GCK, HK3, SI |
| Taurine and hypotaurine metabolism | 1 | 8 | GAD1, CSAD, GLRA1 |
| Cysteine and methionine metabolism | 2 | 33 | CTH, MTR, MTHFR, TAT |
| Caffeine metabolism | 1 | 10 | XDH, HPRT1, PNP |
| Amino sugar and nucleotide sugar metabolism | 2 | 37 | KHK, GAA, MGAM, GANC |
| Arginine and proline metabolism | 2 | 38 | GAMT, GATM |
| Valine, leucine and isoleucine degradation | 2 | 40 | BCAT1, BCAT2, IARS |
| Nicotinate and nicotinamide metabolism | 1 | 15 | QPRT, KMO |
| Starch and sucrose metabolism | 1 | 18 | GCK, HK3, SI |