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. 2022 Mar 14;10(3):671. doi: 10.3390/biomedicines10030671

Table 2.

Plant-derived ingredients that influence the oral microbiome.

Plant Extracts Plants of Essential Oils Biological Activities on Oral Microbiome References
Camellia sinensis Anti-inflammatory, antimicrobial, antioxidant, anti-carcinogenic and anti-allergic [151]
Black tea (teaflavins) Antibacterial activity against S. mutans and Porphyromonas gingivalis [152,153]
Decreases bacteria responsible for
various oral pathologies
[154]
Melaleuca alternifolia and propolis Eradication of Candidate albicans,
Campylobacter gracilis
[155]
Reduces Streptococcus mitis and
Streptococcus sanguis
[155]
Melaleuca alternifolia, Melissa officinalis and Lavandula angustifolia Antibacterial activity against Staphylococcus aureus and Escherichia coli from oral biofilms [156]
Origanum vulgare, Thymus vulgaris and Eugenia caryophyllata Efficient against Actinomyces viscosus, Enterococcus faecalis, Streptococcus oralis, S. sanguinis, S. salivarius and S. mutans [157]
Cymbopogon nardus Efficient against Candida albicans and Staphylococcus aureus biofilms from prosthetic materials [158]
Syzygium aromaticum Good activity against Porphyromonas gingivalis [159]
Citrus aurantium Antimicrobial activity against S. mutans, significant decrease in several virulent genes expressed by S. mutans [159]
Cinnamomum verum
(oil from barks)
Efficient against S. mutans [160]
Cinamomum verum bark, Cinnamomum zeylanicum, Origanum majorana, and Melaleuca alternifolia Efficient against Solobacterium moorei oral bacteria responsible for halitosis [161,162]
Aloysia gratissima, Aloysia triphylla, Alpinia speciose, Artemisia capillaris, Baccharis dracunculifolia, Callitris glaucophylla, Chrysanthemum indicum, Commiphora myrrha, Coriandrum sativum, Cymbopogon citratus, Cyperus articulatus, Elyonurus muticus, Eugenia caryophyllata, Ficus deltoidea, Juniperus communis, Melaleuca alternifolia and Mentha piperita Efficient against anaerobic bacteria Porphyromonas gingivalis and Fusobacterium nucleatum [162]