Skip to main content
. 2022 Mar 3;10(3):601. doi: 10.3390/biomedicines10030601

Table 1.

IC50 values for PTX and Dox in parental and Tx-R triple-negative breast cancer (TNBC) and gastrointestinal stromal tumor (GIST) cell lines.

Chemical Compounds Cell Line Parental Tx-R Fold Increase
PTX (µM) HCC 1806 0.22 ± 0.01 5.4 ± 1 24.5
GIST T-1 <0.01 0.46 ± 0.08 >46
Dox (µM) HCC 1806 0.22 ± 0.004 1.8 ± 0.5 81.8
GIST T-1 0.04 ± 0.005 6.5 ± 1 162.5
BGJ 398 (µM) HCC 1806 12 ± 1.3 17.6 ± 3 1.47
GIST T-1 8.8 ± 1 7.2 ± 0.2 0.82