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. 2021 Sep 24;5(18):3623–3632. doi: 10.1182/bloodadvances.2021004645

Table 2.

Analysis of survival by baseline patient characteristics

PFS OS
Patient characteristic HR 95% CI P * HR 95% CI P *
Male sex 1.19 0.78-1.80 .42 1.44 0.76-2.71 .26
Age 60-69 vs ≥70 y 0.81 0.53-1.23 .31 0.59 0.29-1.06 .07
Advanced stage 1.75 1.14-2.70 .02 1.75 0.92-3.33 .12
Impaired ADLs/instrumental ADLs 2.11 1.03-4.30 .006 3.58 1.42-8.92 <.0001
Geriatric syndrome 1.24 0.70-2.18 .44 2.21 0.88-5.54 .03
CIRS-G total <10 vs ≥10 1.05 0.62-1.77 .87 2.11 0.92-4.85 .03
Multivariable Cox proportional hazards model (backward elimination)
 Impaired ADLs/instrumental ADLs 2.13 1.23-3.69 .007 2.52 1.13-5.58 .02
*

All P values are 2 sided.