Figure 1.

Binding of cadmium in blood plasma. The panels show the results of gel-chromatographic (G75) separation (at +5 °C) of blood plasma from mice at various time points after s.c. injection of a single dose of radiolabeled CdCl₂. (A): 20 min after injection, (B): 96 h after injection, (C): 192 h after injection. At the shorter time (20 min) all Cd appeared in a high molecularweight peak (fractions 12–14). At longer longer times (B,C), when the concentration of Cd in plasma was 9 nanomol/kg, a considerable proportion of plasma Cd was detected in a second peak (fractions 23–24) at the molecular size of MT. Line with dots: radiocadmium, unbroken line optical density 254 nm (OD). (Picture of Original drawing of chromatographic results. Experimental details described in [27]).