Table 1.

Statistical abnormal bulk volume (ABV) comparisons between local patients with GBM and TCIA database as our validation cohort to carry out a pilot study.

	1. Local Patients with GBM		2. TCIA Database with GBM
Parameter	Mean ± SD (Min.–Max.)	95% Confidence Interval-Mean (Lower–Upper Bound)	Mean ± SD (Min.–Max.)	95% Confidence Interval-Mean (Lower–Upper Bound)
Necrosis/ABV	0.23 ± 0.12 (0.05–0.55)	0.18–0.28 **	0.17 ± 0.83 (0.05–0.33)	0.14–0.20 **
Solid/ABV	0.31 ± 0.16 (0.10–0.62)	0.24–0.38 **	0.43 ± 0.15 (0.18–0.84)	0.37–0.49 **
Peritumoral tissue/ABV	0.08 ± 0.02 (0.05–0.11)	0.07–0.08	0.09 ± 0.03 (0.05–0.16)	0.08–0.10
Edema/ABV	0.39 ± 0.21 (0.02–0.74)	0.30–0.48 **	0.31 ± 0.19 (0.02–0.60)	0.24–0.38 **

All differences were significant by repeated-measures analysis of variance with Bonferroni correction. Differences compared with peritumoral tissue/ABV ratio at p ≤ 0.005 (**). SD, standard deviation; Min, minimum; Max, maximum.