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. 2022 Mar 18;14(6):1552. doi: 10.3390/cancers14061552

Figure 1.

Figure 1

Morphological and molecular progression of CRC. (A) A schematic representation of the morphological progression from normal colon epithelium to dysplasia and ultimately invasive carcinoma. (B) Examples of the different morphological stages of CRC development (40× magnification) using H&E stained tissues. The scale bars represent 100 µm. (C) The molecular progression of normal colon epithelium to CRC on the glycomic level. The glycome, shown here as different N-glycosylation traits, change throughout the progression to CRC.