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(A) The basic principle of the DNAzyme with nucleic acid cleavage function. (B) Schematic diagram of previous DNAzyme-based Pb2+ sensor. (C) Schematic diagram of improved DNAzyme-based Pb2+ sensor. Reprinted (adapted) with permission from [103]. Copyright (2003) American Chemical Society. (D) Schematic diagram of DNAzyme-based amplified biosensor. Reprinted (adapted) with permission from [104]. Copyright (2013) American Chemical Society.
