Table 2.
Multiple linear regression results of sleep quality with fatigue and insomnia with fatigue at week 6, month 6, month 12, and month 24.
| Regression | Model | Week Six 1 | Month Six | Month Twelve | Month Twenty-Four | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β 2 | 95% Cl | p Value | β | 95% Cl | p Value | β | 95% Cl | p Value | β | 95% Cl | p Value | ||
| Sleep Quality and Fatigue 3 | Model 1 a | 2.33 | 0.69, 3.97 | 0.006 | 2.83 | 1.37, 4.30 | <0.001 | 2.48 | 0.85, 4.11 | 0.003 | 3.69 | 2.01, 5.37 | <0.001 |
| Model 2 b | 2.53 | 0.86, 4.19 | 0.003 | 2.95 | 1.59, 4.30 | <0.001 | 2.15 | 0.56, 3.74 | 0.008 | 4.11 | 2.44, 5.78 | <0.001 | |
| Model 3 c | 2.66 | 0.93, 4.39 | 0.003 | 2.96 | 1.56, 4.35 | <0.001 | 2.13 | 0.49, 3.78 | 0.012 | 4.11 | 2.38, 5.83 | <0.001 | |
| Exploratory model d | 0.82 | −0.90, 2.54 | 0.345 | 1.18 | −0.18, 2.54 | 0.088 | 0.94 | −0.55, 2.44 | 0.211 | 1.46 | −0.06, 2.98 | 0.060 | |
| Insomnia and Fatigue 3 | Model 1 e | 4.66 | 3.42, 5.90 | <0.001 | 4.56 | 3.16, 5.95 | <0.001 | 5.06 | 3.56, 6.56 | <0.001 | 5.72 | 3.95, 7.49 | <0.001 |
| Model 2 f | 4.56 | 3.35, 5.85 | <0.001 | 4.52 | 3.07, 5.97 | <0.001 | 5.19 | 3.62, 6.76 | <0.001 | 6.06 | 4.26, 7.85 | <0.001 | |
| Model 3 g | 4.50 | 3.25, 5.75 | <0.001 | 4.44 | 2.98, 5.90 | <0.001 | 5.13 | 3.55, 6.71 | <0.001 | 6.06 | 4.26, 7.85 | <0.001 | |
| Exploratory model h | 1.64 | 0.53, 2.75 | 0.004 | 1.21 | 0.01, 2.41 | 0.047 | 1.29 | −0.10, 2.67 | 0.068 | 1.58 | −0.01, 3.18 | 0.052 | |
a Sleep quality. b Sleep quality, time since end of treatment, gender, age. c Sleep quality, time since end of treatment, gender, age, chemotherapy (yes/no), radiotherapy (yes/no). d Sleep quality, time since end of treatment, gender, age, chemotherapy (yes/no), radiotherapy (yes/no), psychological distress. e Insomnia. f Insomnia, time since end of treatment, gender, age. g Insomnia, time since end of treatment, gender, age, chemotherapy (yes/no), radiotherapy (yes/no). h Insomnia, time since end of treatment, gender, age, chemotherapy (yes/no), radiotherapy (yes/no), psychological distress. 1 All beta coefficients in the top of the table represent the association between fatigue scores (dependent variable) per 1-point change of the sleep quality score (independent variable). 2 All beta coefficients in the bottom half of the table represent the association between fatigue scores (dependent variable) per ½ SD of insomnia scores (independent variable). 3 the number of CRC survivors involved in the insomnia and fatigue regression analyses at each timepoint: W6 (n = 386) M6 (n = 343), M12 (n = 283), M24 (n = 199). The number of CRC survivors involved in the sleep quality and fatigue regression analyses at each timepoint: W6 (n = 76), M6 (n = 73), M12 (n = 62), M24 (n = 72).