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Schematic representation of the calcium channels: Calcium channels are a complex of 4–5 distinct subunits. The α1 subunit is the largest subunit and it incorporates the pore region, the voltage sensor and gating apparatus, several channel regulation sites by second messengers, drugs, and toxins. There is an intracellular β subunit, a transmembrane, α2δ subunit complex, and a transmembrane γ subunit.
