FIG. 1.

C60 pretreatment inhibited E. coli-induced death in B6 mice. Groups of 10 B6 mice were inoculated intracerebrally with 5 × 10⁵ E. coli per mouse. Various doses of C60 were administrated i.p. before E. coli injection. Dexamethasone (6 mg/kg of body weight given i.p.) was used as a control treatment. The reagents were given again at 24 and 48 h. The mice were monitored for death every 12 h for 6 days.